Mucopolysaccharides in Synovial Fluid. Detection of Chondroitin Sulphate
نویسندگان
چکیده
منابع مشابه
Synovial fluid chondroitin and keratan sulphate epitopes, glycosaminoglycans, and hyaluronan in arthritic and normal knees.
OBJECTIVES To determine concentrations of chondroitin sulphate (CS) and keratan sulphate (KS) epitopes, glycosaminoglycans (GAGs) and hyaluronan (HA) in knee synovial fluid (SF) from normal subjects and patients with osteoarthritis (OA) or rheumatoid arthritis (RA), to test whether these variables may be used as markers of the OA process. METHODS OA was subdivided into large joint OA (LJOA), ...
متن کاملSynovial fluid chondroitin sulphate epitopes 3B3 and 7D4, and glycosaminoglycan in human knee osteoarthritis after exercise.
OBJECTIVE Walking exercise alleviates some symptoms, such as pain, in patients with mild to moderate knee osteoarthritis (OA). However, a major concern is that weightbearing exercise on osteoarthritic joints may exacerbate articular cartilage degradation. Loading of proteoglycan depleted articular cartilage in vitro increased expression of the chondroitin sulphate epitope 3B3, suggesting that l...
متن کاملDecline after immobilisation and recovery after remobilisation of synovial fluid IL1, TIMP, and chondroitin sulphate levels in young beagle dogs.
OBJECTIVE To monitor the concentration of markers of cartilage and synovium metabolism in the knee (stifle) joint synovial fluid of young beagles subjected to immobilisation and subsequent remobilisation. METHODS The right hind limb of 17 dogs was immobilised in flexion for 11 weeks. Simultaneously, the contralateral left knee was exposed to increased weight bearing. The remobilisation period...
متن کاملChondroitin sulphation patterns in synovial fluid in osteoarthritis subsets.
OBJECTIVES To determine concentrations of chondroitin sulphate (CS) disaccharides in knee synovial fluid (SF) from normal subjects and patients with osteoarthritis (OA) or rheumatoid arthritis (RA), to test whether these variables differ between different diseases and subsets of OA. METHODS OA was subdivided into large joint OA (LJOA), nodal generalised OA (NGOA), and OA with calcium pyrophos...
متن کاملMucopolysaccharides in synovial fluid. Effect of aspirin and indomethacin on hyaluronic acid.
Intra-articular inflammation is associated with a reduction in viscosity of synovial fluid which is due to changes in hyaluronic acid rather than in the protein component of the fluid (Kulonen, 1951; Sundblad, 1953). Hyaluronic acid is a polymer of molecular weight greater than 1 x 106 made up from repeating units of N-acetyl-D-glucosamine and D-glucuronic acid. It is present in concentrations ...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1966
ISSN: 0003-4967,1468-2060
DOI: 10.1136/ard.25.3.209